منابع مشابه
Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons
In addition to dopaminergic neuron loss, it is clear that Parkinson disease includes other pathological changes, including loss of additional neuronal populations. As a means of addressing multiple pathological changes with a single therapeutically-relevant approach, we employed delayed transplantation of a unique class of astrocytes, GDAs(BMP), that are generated in vitro by directed different...
متن کاملExperiments in a Parkinson's rat model.
ously unpublished) family of southern Bavarian origin showed positive lod scores with a maximum multipoint score of 1.5 (family K, Fig. 1). This lod score is close to the theoretical maximum in this relatively small family. In six families (FR-041, FR-722, FR-727, FR-755, UK-A, and UK-B), only the two polymorphic markers most closely linked to PD1 (D4S1647 and D4S2380) have been analysed. Oblig...
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Objective(s): The present work intended to clearly define the most adequate humane endpoints in an experimental assay of mammary carcinogenesis in rats. Materials and Methods: Animals were observed twice a day; all parameters were registered once a week and the euthanasia endpoints were established in order to monitor the animal welfare/...
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Assessment of the cellular effects of natural and/or synthetic products is one of the major goals in biological experiments. This assessment may be conducted at different levels; cellular viability, cellular biological activity, and cellular structure and morphology. Different assays are available for any of above purposes. It is becoming of a routine exercise to apply any of these assays, and ...
متن کاملTwo-Stage Nerve Graft in Severe Scar: A Time-Course Study in a Rat Model
excessive scarring; paralleling the process in tendon reconstruction of the hand. Inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. Methods: Thirty female rats (~200 g) were randomly distributed into two groups (n=15...
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ژورنال
عنوان ژورنال: Science
سال: 1997
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.277.5324.389